P16 Immunostain Pathology, Positive & Negative Meaning, Staining

P16 Immunostain Pathology, Positive & Negative Meaning, Staining

In biochemistry, immunostaining refers to a technique that uses an antibody-based method to detect a particular protein in the sample. This term earlier described immunohistochemical staining of tissue sections by Albert Coons in 1941. The principle of this technique is to detect an antigen in the tissues or cells by …

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Trichilemmal Cyst Symptoms, Causes, Diagnosis, Treatment

Cyst

A trichilemmal cyst is also known as a pilar, wen, or isthmus-catagen cyst. This cyst forms a hair follicle on the scalp most of the time and is visibly mobile, smooth, and filled with cytokeratin. Cytokeratin is a protein present in nails, hair, horns, and skin.  A trichilemmal cyst is …

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Venous Angioma Symptoms, Causes, Diagnosis, Treatment

Venous Angioma Symptoms, Causes, Diagnosis, Treatment

Angiomas or developmental venous anomalies (DVA) refer to a set of benign tumors derived from cells of the endothelium or the tissues surrounding these vessels. These tumors may be an indication of systemic problems such as liver disease. However, angiomas are usually not associated with malignancy. They represent the concept …

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Nitroglycerin vs Nitroprusside Mechanism, Indications, Side Effects

Nitroglycerin vs Nitroprusside Mechanism, Indications, Side Effects

Nitroglycerin medications are extended-release capsules that belong to a class of drugs, nitrates that reduce chest pain or angina in individuals affected with a heart condition associated with the coronary artery. The cause of angina is the heart muscle’s inability to receive enough blood. This medication functions by widening the …

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Wilkie’s Syndrome Symptoms, Causes, Surgery, Life expectancy

Wilkie's Syndrome Symptoms, Causes, Surgery, Life expectancy

Wilkie’s syndrome or superior mesenteric artery syndrome (SMA) is a kind of gastro-vascular disorder. It is an acquired disorder in which acute angulation of the superior mesenteric artery occurs. This gastrointestinal disorder is rare; it is present in approximately 0.013–0.3% of the general population. The condition is characterized; by vascular …

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Ink Spot Lentigo Symptoms, Causes, Dermoscopy, Removal

Ink Spot Lentigo Symptoms, Causes, Dermoscopy, Removal

A lentigo refers to a flat pigment or slightly raised lesion having a clearly defined edge. A lentigo is quite similar to a small-sized lentil and is distinguishable from freckle or ephelis as it does not disappear during the winter season. There are various kinds of lentigo observed in individuals. …

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Solar Lentigo Symptoms, Causes, Dermoscopy, Treatment

Solar Lentigo Symptoms, Causes, Dermoscopy, Treatment

A lentigo is a sharp, little circumcised, pigmented macule surrounded by normal skin. Individuals with lentigo may exhibit histologic findings that may involve increased basal layer pigmentation and hyperplasia of the epidermis. There are various types of lentigo depending upon the cause and where they appear on the human body. …

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Pseudopapilledema Symptoms, Causes, Diagnosis, Treatment

Pseudopapilledema Symptoms, Causes, Diagnosis, Treatment

Pseudopapilledema is a medical condition that refers to the irregular elevation of one or both optic discs without edema of the retinal nerve fiber layer. The retinal fiber layer is formed; by optic nerve fibers expansion. The sparing of this layer is of vital importance in disease treatment; it serves …

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Periventricular Leukomalacia in Symptoms, Stages, Causes, Treatment

Periventricular Leukomalacia in Symptoms, Stages, Causes, Treatment

PVL or periventricular leukomalacia is the softening of; the white brain tissue near the ventricles. These ventricles are fluid-filled; they contain CSF or cerebrospinal fluid. This white matter is the inner part of the brain. It is a brain injury characterized by necrosis or coagulation of white matter near the …

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Precarinal Lymph Node Location, Size, Enlargement, Cancer

Precarinal Lymph Node Location, Size, Enlargement, Cancer

Lymph nodes are the small bean-shaped structures responsible for the immunity of the body. These lymph nodes must filter those substances that pass through the lymphatic fluid. The lymph nodes contain lymphocytes or white blood cells. These lymphocytes present in the lymph nodes are responsible for the body’s protection against …

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