Functional Residual Capacity Definition, Importance, Volume, COPD

Learn all about functional residual capacity definition, importance, volume and chronic obstructive pulmonary (COPD).

The volume of gas in the lungs at the end of a normal tidal volume exhalation is called functional residual capacity. The functional residual capacity is equal to the residual volume plus the expiratory reserve volume.

Factors that alter FRC include body habitus, , posture, disease, and diaphragmatic tone. Induction of anesthesia produces an additional 15-20% reduction in FRC beyond what occurs in the supine position alone.

A symptomatic decrease in FRC, resulting in hypoxemia, is the main indication for positive airway pressure therapy. By increasing transpulmonary distending pressure, positive airway pressure therapy can increase FRC, improve (increase) lung compliance, and reverse ventilation/perfusion mismatching.

The major effect of PEEP on the lungs is to increase FRC. In patients with decreased lung volume, both PEEP and CPAP increase FRC and tidal ventilation above closing capacity, improves lung compliance, and correct ventilation/perfusion abnormalities. The resulting decrease in intrapulmonary shunting improves arterial oxygenation.

Functional Residual Capacity Definition, Importance, Volume, COPD

What is Functional Residual Capacity?

Functional residual capacity (FRC) refers to the volume of air left in the lungs after a normal, passive exhalation. It is used to evaluate the elasticity of the lungs and chest wall in persons with respiratory illnesses like chronic obstructive pulmonary disease (COPD).

Functional Residual Capacity Definition

Functional residual capacity (FRC) is the volume of the respiratory system when the respiratory muscles are relaxed and no external forces are applied. It is the volume of the lung at the end of a normal expiration. FRC is the volume at which the inward recoil of the lung is exactly balanced by the outward recoil of the chest wall.

Functional Residual Capacity Importance

When you exhale, you don’t expel all of the air from your lungs. Some will remain after exhalation in order to maintain elasticity of the organ. The retained air (known as functional residual volume) allows the lungs to fill with less effort while keeping the elastic forces of inhalation and exhalation in balance. Without this balance, the interchange between oxygen and carbon dioxide in our alveoli would vary, sometimes significantly. There are two reasons for the existence of FRC:

After tidal respiration the gas remaining inside lungs prevents collapse of alveoli. If after each expiration the alveoli collapse then the force required to reinflate them would be much larger with liquid-liquid interface than that to inflate partially filled alveoli with liquid-gas interface.
The gas in the alveoli acts as a buffer. The inspired gas mixes with alveolar gas and allows a constant concentration of gases in the alveoli. If this gas is not present, then there would be large fluctuations in alveolar gas concentrations and similar variations in blood gases.

Functional Residual Capacity Volume

The functional residual capacity (FRC), about 2,400 mL, is the amount of air remaining in the lungs after a normal expiration (FRC = RV + ERV). Average functional residual capacity in males is 2.3 litres and in females is 1.8 litres.

Functional Residual Capacity COPD

FRC or the lung volume at the end of quiet expiration during tidal breathing (i.e., EELV) is increased in COPD compared with health. The term EELV is used interchangeably with FRC in the current review. It should be noted that FRC is not always synonymous with the static equilibrium volume of the relaxed respiratory system; Vr is the volume at which the elastic recoil pressures of lung and relaxed chest wall are equal and opposite in sign. Active or passive mechanisms often operate to make FRC different from Vr both in health and in COPD. For example, in healthy younger subjects during exercise, activation of expiratory muscles commonly drives FRC below the Vr. An increase in FRC measured at rest has both static and dynamic determinants in COPD. Traditionally, an increase in “static” FRC refers to an increase in Vr due to loss of lung recoil which resets the balance of forces between the lung and chest wall.

Accordingly, the static Vr is higher than that of predicted normal and FRC is increased in COPD compared with health. In this circumstance the higher Vr means that the alveolar pressure at end-expiration remains atmospheric. Interestingly, resting FRC is also dynamically determined in the setting of EFL and varies with the breathing pattern. For instance, a tachypneic breathing pattern and/or a high inspiratory-to-expiratory time ratio will shorten the time available for adequate lung emptying. Thus, mouth pressure at EELV is positive a phenomenon termed intrinsic positive end-expiratory pressure (PEEP). EELV during spontaneous breathing in flow-limited patients is a continuous dynamic variable. DH can therefore occur when, V˙E or breathing frequency are abruptly increased (e.g., voluntarily, during anxiety/panic attacks, acute hypoxemia, physical activity or during metronome pacing) or EFL is suddenly worsened (e.g., increased bronchospasm or during exacerbation. Lung hyperinflation at rest is also influenced by body position and by body mass: for example, EELV decreases when adopting a supine position or with obesity. In this respect, FRC has been shown to decrease exponentially with increasing body mass index (BMI), with the largest changes occurring with BMI in the overweight to mild obesity range.

One comment

  1. Edward Sheaver

    I was diagnosed with COPD 5 years ago and was taking Spiriva and Advair plus nose sprays to slow down progression. My symptoms have always been shortness of breath, and dizziness. I am a 54 year old male. the Spiriva wasn’t really working and I could not tolerate them for long due to severe side effects, so this year our family doctor started me on Natural Herbal Gardens COPD Herbal mixture, We ordered their COPD herbal treatment after reading alot of positive reviews, i am happy to report with the help of Natural Herbal Garden natural herbs I have been able to reverse my symptoms using herbs, my symptoms totally declined over a 9 weeks use of the Natural Herbal Gardens COPD natural herbal formula. My COPD is totally reversed! Their official web page is naturalherbalgardens . c o m After the herbal treatment I also finally was able to give up smoking after 20 years. I ‘m thankful to nature

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