Learn all about prostatodynia definition, symptoms, causes, treatment and syndrome
Prostatodynia is a very common disease and accounts for a large share of cases presented in urology; it is even considered the most common urologic disease in men younger than 50 years.
It has been estimated that up to half of all men suffer from prostatitis at least once in their life; most likely when aged 35 to 50 years. Thus, it does not come as a surprise that millions of cases are diagnosed each year.
Only 5% to 10% of the cases can be classified as bacterial CP. The remaining cases are termed non-bacterial and may be provoked by different conditions. However, in addition to the symptom of pelvic pain, many men suffering from chronic abacterial prostatitis/prostatodynia also complain of associated lower urinary tract symptoms and ejaculatory discomfort.
Consequently treatment with tadalafil at a dose of 5 mgs per day for a period of time would seem logical. It could be surmised that many of its beneficial effects might stem from an improvement of blood flow to pelvic organs as a consequence of its anti-inflammatory and vasodilatory activity, as well as a relaxant effect on smooth muscle, as has been previously suggested in the case of lower urinary tract symptoms by Karl-Eric Andersson and others.
What is Prostatodynia?
Prostatodynia is typically a chronic, painful disease. Prostatodynia is an uncommon cause of perineal pain in men. Also known as chronic nonbacterial prostatitis and chronic pelvic pain syndrome, prostatodynia probably is not a single clinical entity, but rather the conglomeration of a variety of disorders that can cause pain in this anatomical region.
A type of inflammation of the prostate not due to bacterial infection and in which there are no objective findings, such as the presence of infection-fighting cells, in the urine of men who suffer from the disease. The prostate is a walnut-sized organ below the male bladder that surrounds the urethra and contributes fluid to the semen.
This pain is associated with irritative voiding symptoms and/or pain located in the groin, genitalia, or perineum in the absence of pyuria and bacteriuria (no pus cells or bacteria seen on microscopic analysis of the urine). However, excess white blood cells (WBCs) or bacteria seen on Gram stain and culture of expressed prostatic secretions (EPS) may be found.
Bacteria most often reach the prostate by ascending through the urethra. Other, less probable sources of infection may be bladder, bowel, blood and lymph. Gram-negative bacteria such as Escherichia coli (E. coli), Klebsiella, Proteus and Pseudomonas may trigger prostatitis, but gram-positive bacteria such as Enterococcus have also been isolated. E. coli are by far the most common causative agents. In contrast to E. coli strains responsible for uncomplicated urinary infections, it has been proposed that E. coli strains provoking CP are more virulent and tend to produce biofilms. This would explain why they are rather difficult to eliminate and why the corresponding acute cases of prostatitis become often chronic.
Prostatodynia treatment depends on the severity of disease. Rye grass is a plant. The rye grass pollen is used to make medicine. Rye grass pollen extract (Cernilton) is a registered pharmaceutical product in Western Europe, Japan, Korea, and Argentina. Rye grass is used for prostate conditions such as benign prostatic hyperplasia (BPH), prostate pain, and ongoing inflammation of the prostate. Rye grass decreases swelling (inflammation) by interfering with certain chemicals. It might also slow down prostate cancer cell growth Alpha blockers are the medications most likely to reduce symptoms of prostatodynia or non-inflammatory prostatitis.
A review published in Urologia Internationalis found that alpha blockers were more likely to be effective for men who were newly diagnosed with chronic pelvic pain syndrome; that an extended course of treatment (three to six months) was more effective than a shorter course; and that broader alpha blockers such as doxazosin (Cardura) and terazosin (Hytrin) were more effective than the more selective agents.. Cernilton was found to be effective in the treatment of chronic prostatitis and prostatodynia. Its precise mode of action is not known, although experimental studies suggest that it has anti-inflammatory and anti-androgenic properties.
Chronic Pelvic Pain Syndrome is a chronic inflammation that occurs in the prostate gland which is painful but is not due to a bacterial infection although at the initial onset of pain prostatitis could have been present and properly treated. It is also sometimes referred to as Chronic Non-Bacterial Prostatitis, Category III Chronic Prostatitis, and used to be called Prostatodynia. Men with Chronic Pelvic Pain Syndrome have pelvic floor muscle dysfunction which many times is the source of the pain. The pelvic floor muscles surround the genitals and anus as a support structure for the organs, help maintain continence, provide lumbo-pelvic stability and aid in erectile function and ejaculation.